論文リスト 2000年以降      1999年以前 こちら
                      歴代院生論文発表回数ランキング こちら
                   当研究室に所属する前の論文リスト 小林 こちら 川本 こちら

 

78. Yuichiro Kawamoto, Toyoharu Kobayashi, and Hisanaka Ito, Asymmetric Total Synthesis of Stachyodins A and B, Tetrahedron in press. 
77. Yuichiro Kawamoto, Naoki Noguchi, Daiki Ozone, Toyoharu Kobayashi, and Hisanaka Ito, Convenient preparation of synthetically useful chiral quaternary carbon-containing bicyclic compounds with organocatalysts, Tetrahedron Lett. 2021, 85, 153495.
76. Takeshi Yamamotoya, Yusuke Nakatsu, Shun Hasei, Yukino Ohata, Jeffrey Encinas, Hisanaka Ito, Takayoshi Okabe, Tomoichiro Asano, and Takemasa Sakaguchi, Prolyl isomerase Pin1 plays an essential role in SARS-CoV-2 proliferation, implicating the possibility as a novel therapeutic target, Sci. Rep. 2021, 11, 18581.  
75. Yuichiro Kawamoto, Hideki Kitsukawa, Toyoharu Kobayashi, and Hisanaka Ito, Total Synthesis of Nesteretal A, Org. Lett. 2021, 23, 7074-7078. 
74. Akinobu Kamiya, Yuichiro Kawamoto, Toyoharu Kobayashi, and Hisanaka Ito, Total Synthesis of ent-Callilongisin B, Org. Lett. 2021, 23, 6916-6918.
73. Yasuka Matsunaga, Shun Hasei, Takeshi Yamamotoya, Hiroaki Honda, Akifumi Kushiyama, Hideyuki Sakoda, Midori Fujishiro, Hikaru Ono, Hisanaka Ito, Takayoshi Okabe, Tomoichiro Asano, and Yusuke Nakatsu, Pathological role of Pin1 in the development of DSS-induced colitis, Cells 2021, 10, 1230.  
72. Yuichiro Kawamoto, Toyoharu Kobayashi, and Hisanaka Ito, Total Synthesis of Stachyodin A via One-Pot Suzuki Coupling for Quick Construction of Carbon Skeleton, Org. Lett. 2021, 23, 3864-3867.  
71. Yuichiro Kawamoto, Fuka Karube, Toyoharu Kobayashi, and Hisanaka Ito, Stereocontrolled Asymmetric Synthesis of Mollebenzylanols A and B Using Claisen Rearrangements, Tetrahedron 2021, 83, 131958.    
70. Kyohei Uchida, Yuichiro Kawamoto, Toyoharu Kobayashi, and Hisanaka Ito, Total Synthesis of Applanatumols X and Y, Tetrahedron Lett. 2020, 61, 152611.
69. Yuichiro Kawamoto, Fuka Karube, Toyoharu Kobayashi, and Hisanaka Ito, Enantioselective Total Synthesis of Mollebenzylanol A, Org. Lett. 2020, 22, 7609-7612.
68. Yuki Miyamoto, Marina Tanaka, Hisanaka Ito, Hiroaki Ooizumi, Katsuya Ohbuchi, Kazushige Mizoguchi, Tomohiro Torii, and Junji Yamauchi, Expression of kinase-deficient MEK2 ameliorates Pelizaeus-Merzbacher disease phenotypes in mice, Biochem. Biophys. Res. Commun. 2020, 531, 445-451.
67. Toyoharu Kobayashi, Yui Tomita, Yuichiro Kawamoto, and Hisanaka Ito, Highly Stereocontrolled Total Synthesis of Secodolastane Diterpenoid Isolinearol, Org. Biomol. Chem. 2020, 18, 7316-7320.  
本論文のグラフィックがOrganic & Biomolecular Chemistry誌の表紙を飾りました.こちら
本論文がOrganic Chemistry Portalで紹介されました. こちら
66. Yuichiro Kawamoto, Daiki Ozone, Toyoharu Kobayashi, and Hisanaka Ito, Enantioselective total synthesis of chondrosterins I and J via catalytic aymmetric intramolecular aldol reaction using chiral diamine catalyst, Euro. J. Org. Chem. 2020, 4050-4058.
本論文がOrganic Chemistry Portalで紹介されました. こちら
65. Yusuke Nakatsu, Yasuka Matsunaga, Koji Ueda, Takeshi Yamamotoya, Yuki Inoue, Masaki Inoue, Yu Mizuno, Akifumi Kushiyama, Hiraku Ono, Midori Fujishiro, Hisanaka Ito, Takayoshi Okabe, Tomoichiro Asano, Development of Pin1 inhibitors and their potential as therapeutic agents, Current Medicinal Chemistry, 2020, 27, 3314-3329.
64. Toyoharu Kobayashi, Iori Takizawa, Yuichiro Kawamoto, and Hisanaka Ito, Sequential Condensation-6π-electrocyclization Reaction of a Chiral 1,3-Diketone Possessing C2 Symmetry, Tetrahedron Lett. 2020, 61, 151897.
本論文のグラフィックがTetrahedron Letters誌の表紙を飾りました. こちら
63. Toyoharu Kobayashi, Hideki Abe, and Hisanaka Ito, Synthetic Studies of Polycyclic Terpenoids Using Intramolecular Aldol Type Cyclization Reaction, J. Synth. Org. Chem. Jpn. 2019, 77, 1086-1095.  
62. Kyohei Uchida, Yuichiro Kawamoto, Toyoharu Kobayashi, and Hisanaka Ito, Total Synthesis of Applanatumol B, Org. Lett. 2019, 21, 6199-6201.
61. Yuichiro Kawamoto, Toyoharu Kobayashi, and Hisanaka Ito, Enantioselective Total Synthesis of Diocollettines A, Org. Lett. 2019, 21, 5813-5816. 
60. Hideki Abe, Saki Sato, Wakana Oishi, Mei Tamura, Toyoharu Kobayashi, and Hisanaka Ito, Total synthesis of the tricyclic humulanolide wilfolide B, Tetrahedron Lett. 2019, 60, 2059-2062. 
59. Hideki Abe, Mitsuru Fujimaki, Ena Goto, Akihito Yokosuka, Yoshihiro Mimaki, Toyoharu Kobayashi, and Hisanaka Ito, Total synthesis and determination of the absolute configuration of paralemnolin C and biological studies of eremophilane derivatives, Tetrahedron Lett. 2019, 60, 1604-1606.  
58. Toyoharu Kobayashi, Iori Takizawa, Ayumu Shinobe, Yuichiro Kawamoto, Hideki Abe, and Hisanaka Ito, Development of a Chiral Diketone Possessing C2 Symmetry: Asymmetric Synthesis and Structure Revision of Guignardone H and I Using Sequential Condensation-6π-Electrocyclization Reactions, Org. Lett. 2019, 21, 3008-3012.  
本論文のグラフィックがOrganic Letters誌の表紙を飾りました.こちら
本論文がOrganic Chemistry Portalで紹介されました.こちら
57. Yuichiro Kawamoto, Daiki Ozone, Toyoharu Kobayashi, and Hisanaka Ito, Total Synthesis of (±)-Chondrosterin I Using Desymmetric Intramolecular Aldol Reaction, Org. Biomol. Chem. 2018, 16, 8477-8480.  
56. Toyoharu Kobayashi, Konomi Tanaka, Masako Ishida, Natsumi Yamakita,  Hideki Abe, and Hisanaka Ito, Asymmetric Total Synthesis of Pleurospiroketals A and B, Chem. Commun. 2018, 54, 10316-10319.  
55. Hideki Abe, Mitsuru Fujimaki, Eri Nakagawa, Toyoharu Kobayashi, and Hisanaka Ito, Enantioselective total synthesis of sagittacin E and related natural products, Chem. Commun. 2018, 54, 6165-6168.  
本論文の不斉非対称化反応がOrganic Chemistry Portalで紹介されました. こちら
54. Hideki Abe, Takuma Hikichi, Kosuke Emori, Akihito Yokosuka, Yoshihiro Mimaki, Toyoharu Kobayashi, and Hisanaka Ito, Total Synthesis of Catunaregin and Preliminary Evaluation of its Antitumor Activity, Euro. J. Org. Chem. 2018, 1655-1664.  
本論文がOrganic Chemistry Portalで紹介されました.こちら
53. Toyoharu Kobayashi, Kotono Yamanoue, Hideki Abe, and Hisanaka Ito, Diastereoselective Total Synthesis of (±)-Toxicodenane A, Euro. J. Org. Chem. 2017, 6693-6699.  
本論文がOrganic Chemistry Portalで紹介されました.こちら
52. Hideki Abe, Yuta Ogura, Toyoharu Kobayashi, and Hisanaka Ito, Total Synthesis of Paralemnolide A, Org. Lett. 2017, 19, 5996-5999.  
本論文がOrganic Chemistry Portalで紹介されました. こちら
51. Hideki Abe, Haruhito Tango, Toyoharu Kobayashi, and Hisanaka Ito, Asymmetric total synthesis and revision of absolute configurations of azaphilone derivative felinone A, Tetrahedron Lett. 2017, 58, 4296-4298. 
50. Toyoharu Kobayashi, Masako Ishida, Kazuhiro Imaida, Hideki Abe, and Hisanaka Ito, Total Synthesis of Pleurolactone, Tetrahedron Lett. 2017, 58, 3294-3295.  
49. 小林豊晴,阿部秀樹,伊藤久央,「ラジカルを制御して複雑分子を一挙に組み立てる」-ラジカル反応を利用した最新の天然物合成-(総説),化学 2016, 71, No.9, 66-67. 
48. Toyoharu Kobayashi, Ryuta Shioi, Ai Ushie, Hideki Abe, and Hisanaka Ito, Catalytic Asymmetric Total Synthesis of Artalbic Acid, Chem. Commun. 2016, 52, 9391-9393.
47. Hideki Abe, Takuma Hikichi, Kosuke Emori, Toyoharu Kobayashi, and Hisanaka Ito, Concise Asymmetric Total Synthesis of Catsunaregin, Org. Chem. Front. 2016, 3, 1084-1086. 
46. Hideki Abe, Satoko Itaya, Kei Sasaki, Toyoharu Kobayashi, and Hisanaka Ito, Enantioselective Total Synthesis of the Proposed structure of Furan-Containing Polyketide, Chem. Pharm. Bull. 2016, 64, 772-777
45. Hideki Abe, Tomoyuki Morishita, Toshihiro Yoshie, Kerya Long, Toyoharu Kobayashi, and Hisanaka Ito, First Total Synthesis of (±)-Naupliolide: A Novel Tetracyclic Sesquiterpene Lactone, Angew. Chem. Int. Ed. 2016, 55, 3795-3798.  

本論文がSynfacts誌で紹介されました.https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0035-1562027
44. Toyoharu Kobayashi, Kasumi Tokumoto, Yuki Tsuchitani, Hideki Abe, and Hisanaka Ito, Synthetic study of marine diterpenoid aberrarone: stereocontrolled construction of tetracyclic framework, Tetrahedron 201571, 5918-5924. 
43. Hideki Abe, Yuri Horii, Megumi Hagiwara, Toyoharu Kobayashi, and Hisanaka Ito, Stereoselective synthesis of a highly oxygenated decahydrocyclopenta[g]chromene derivative: the common tricyclic framework of leucosceptrine and leucosesterterpenone, Chem. Commun. 2015, 51, 6108-6110. 

42. Hideki Abe, Satoko Itaya, Kei Sasaki, Toyoharu Kobayashi, and Hisanaka Ito, Total synthesis of the proposed structure of a polyketide from Phialomyces macrosporus, Chem. Commun. 2015, 51, 3586-3589. 

41. Hideki Abe, Naohiro Miyagawa, Sho Hasegawa,Toyoharu Kobayashi, Sakae Aoyagi, Chihiro Kibayashi, Tadashi Katoh, and Hisanaka Ito, Directed synthesis of 2-spiroindolines from indole derivatives by formic acid-induced N-acyliminiumion-conjugated diene spirocyclization, Tetrahedron Lett. 2015, 56, 921-924. 

40. Hideki Abe, Toshihiro Yoshie, Takumi Wagatsuma,Toyoharu Kobayashi, and Hisanaka Ito, Synthetic Study of Afritoxinone A: Stereoselective Construction of Furopyranone Moiety, Heterocycles 2015, 90, 706-714. 

39. Toyoharu Kobayashi, Yutaro Kon, Hideki Abe, and Hisanaka Ito,  Concise Total Synthesis of Albaflavenone utilizing Sequential Intramolecular Aldol Condensation: Determination of Absolute Configuration, Org. Lett. 201416, 6397-6399. 

38. Hideki Abe, Akira Tezuka, Toyoharu Kobayashi, Hisanaka Ito, Synthesis of Oxygen-Bridged Decahydroazulene Derivatives: Simplified Analogues of Biologically Active Natural Products, Heterocycles 201488, 651-662.

37. Toyoharu Kobayashi, Hidenori Shiroi, Hideki Abe, and Hisanaka Ito, Synthetic Study of Presilphiperfolan-8-ol: Construction of the Tricyclo[5.3.1.04,11]undecane Framework Utilizing Intramolecular Aldol Condensation and McMurry Coupling, Chem. Lett. 2013,42, 975-976.

36. Hideki Abe, Akimi Sato, Toyoharu Kobayashi, and Hisanaka Ito, Concise Total Synthesis of Spirocurcasone, Org. Lett. 201315, 1298-1301.

本論文がSynfacts誌で紹介されました.https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0033-1338712
35. Hideki Abe, Naoki Fukazawa, Toyoharu Kobayashi, and Hisanaka Ito, Indium chloride mediated chlorolactonization: Construction of chlorinated lactone fragments, Tetrahedron 201369, 2519-2523.

34. Hideki Abe, Akimi Sato, Shin-ichi Tokishita, Toshihiro Ohta, and Hisanaka Ito, Synthesis of Fluorescence Pyriproxyfen Analogues as Juvenile Hormone Agonist, Heterocycles 201183, 1649-1658.

33. Yohei Ueda, Hideki Abe, Kazuo Iguchi, and Hisanaka Ito, Synthetic study of yonarolide: stereoselective construction of the tricyclic core, Tetrahedron Lett. 201152, 3379-3381.

32. Yohei Ueda, Kayoko Iwahashi, Kazuo Iguchi, and Hisanaka Ito, Enantioselective Synthesis of the Tetracyclic Core of Platensimycin, Synthesis 2011, 1532-1536.

31. Hisanaka Ito, Mai Matsuoka, Yohei Ueda, Madoka Takuma, Yoshihisa Kudo, and Kazuo Iguchi, Quinolinecarboxylic Acid Based Fluorescent Molecules: Ratiometric Response to Zn2+, Tetrahedron 2009, 65, 4235-4238.

30. Hisanaka Ito, Takaya Inoue, and Kazuo Iguchi, Toward the Synthesis of Didemnaketal B: A Convergent Synthesis of the C9-C28 Subunit, Org. Lett. 200810, 3873-3876.

29. Hisanaka Ito, Junya Iwasaki, Yuki Sato, Miwako Aoyagi, Kazuo Iguchi, and Takao Yamori, Marine Diterpenoids with a Briarane Skeleton from the Okinawan Soft Coral Pachyclavularia violacea, Chem. Pharm. Bull. 200755, 1671-1676.

28. 伊藤久央,佐藤 梓,田口武夫, γ,γ-ジアルコキシアリルジルコニウム種を用いた炭素-炭素結合形成反応の開発, 有機合成化学協会誌 200765, 56-64. 

27. Yosuke Takenaka, Hisanaka Ito, and Kazuo Iguchi, Enantioselective formal synthesis of (+)-precapnelladiene by chiral copper catalyzed asymmetric [2+2]-cycloaddition reaction, Tetrahedron 2007, 63, 510-513.

26. Hisanaka Ito, Shunta Takeguchi, Takahiro Kawagishi, and Kazuo Iguchi, Total Synthesis of (±)-Clavubicyclone, Org. Lett. 20068, 4883-4885. 

25. Hisanaka Ito, Tsutomu Momose, Masami Konishi, Eriko Yamada, Kinzo Watanabe, and Kazuo Iguchi, Enantioselective total synthesis of both diastereomers of preclavulone-A methyl ester, Tetrahedron 2006, 62, 10425-10433. 

24. Yosuke Takenaka, Hisanaka Ito, Mineki Hasegawa, and Kazuo Iguchi, Catalytic enantioselective [2+2]-cycloaddition reaction of 2-methoxycarbonyl-2-cyclopenten-1-one by chiral copper catalyst, Tetrahedron 200662, 3380-3388. 

23. Junya Iwasaki, Hisanaka Ito, Mitsutake Nakamura, and Kazuo Iguchi, Synthetic studies of briarane-type marine diterpenoid, pachyclavulide B, Tetrahedron Lett. 200647, 1483-1486. 

22. Junya Iwasaki, Hisanaka Ito, Miwako Aoyagi, Yuki Sato, and Kazuo Iguchi, Briarane-type Diterpenoids from the Okinawan Soft Coral, Pachyclavularia violacea, J. Nat. Prod. 200669, 2-6. 

21. Hisanaka Ito, Chie Kawabe, and Kazuo Iguchi, Construction of Optically Active Spiroketal by Direct Aldol Reaction, Heterocycles 2006, 67, 695-704.  (Prof. Trost’s 65th birthday special issue)

20. Azusa Sato, Hisanaka Ito, Midori Okada, Yuko Nakamura, and Takeo Taguchi, Copper-catalyzed addition of γ,γ-dialkoxyallylic zirconium species with imines, Tetrahedron Lett. 200546, 8381-8383.

19. Hisanaka Ito, Azusa Sato, and Takeo Taguchi, The Lewis acid promoted reactions of γ,γ-dialkoxyallylic zirconium species with various carbonyl compounds, Tetrahedron 2005, 61, 10868-10879.

18. Hisanaka Ito, Yosuke Takenaka, Shouhei Fukunishi, and Kazuo Iguchi, A Practical Preparation of 2-Hydroxymethyl-2-cyclopenten-1-one by Morita-Baylis-Hillman Reaction, Synthesis 2005, 3035-3038.

17. Azusa Sato, Hisanaka Ito, and Takeo Taguchi, Highly Regioselective Coupling Reactions of Allylic and Propargylic Alcohol Derivatives with γ,γ-Dialkoxyallylic Zirconium Species via Zr-to-Cu Transmetalation, J. Org. Chem. 200570, 709-712. 

16. Yasushi Takigawa, Hisanaka Ito, Katsunori Omodera, Minoru Koura, Yasuyuki Kai, Emi Yoshida, and Takeo Taguchi, Diastereoselective Intramolecular Ester Transfer Reaction of N-alkenylcarbamate Derivatives Mediated by Zirconocene-butene Complex. Preparation of a,g-Disubstituted γ-Aminobutyric acid (GABA) Derivatives and 2,4-Disubstituted Pyrrolidine Derivatives, Synthesis 2005, 2046-2054. 

15. Hisanaka Ito, Mineki Hasegawa, Yosuke Takenaka, Tatsuya Kobayashi, and Kazuo Iguchi, Enantioselective Total Synthesis of (+)-Tricycloclavulone, J. Am. Chem. Soc. 2004126, 4520-4521. 

14. Yasushi Takigawa, Hisanaka Ito, Katsunori Omodera, Maiko Ito, and Takeo Taguchi, Construction of nitrogen-heterocyclic compounds through zirconium mediated intramolecular alkene-carbonyl coupling reaction of N-(o-alkenylaryl)carbamate derivatives, Tetrahedron 200460, 1385-1392. 

13. Hisanaka Ito, Masami Konishi, and Kazuo Iguchi, Stereoselective Total Synthesis of Preclavulone-A Methyl Ester and Its Diastereomer, Tetrahedron Lett. 200445, 1941-1944. 

12. 伊藤久央, ジルコノセン錯体を用いた新規炭素-炭素結合形成反応の開発, 薬学雑誌 2003123, 933-948. 

11. Hisanaka Ito, Tatsuya Kobayashi, Mineki Hasegawa, and Kazuo Iguchi, An efficient constructive method for a tricyclic system: an important intermediate for the synthesis of tricycloclavulone, Tetrahedron Lett. 200344, 1259-1261.

10. Akio Saito, Hisanaka Ito, and Takeo Taguchi, Intramolecular Diels-Alder Reactions of Ester-Tethered 1,7,9-Decatrienoates: Bis[chloro(methyl)aluminum] trifluoromethanesulfonamide as a Catalyst, Org. Lett. 20024, 4619-4621.

9. Barry M. Trost, Vince S. C. Yeh, Hisanaka Ito, and Nadine Bremeyer, Effect of Ligand Structure on the Zinc-Catalyzed Henry Reaction. Asymmetric Syntheses of (-)-Denopamine and (-)-Arbutamine, Org. Lett. 20024, 2621-2623.

8. Hisanaka Ito, Katsunori Omodera, Yasushi Takigawa, and Takeo Taguchi, 1 Zirconium-Mediated Intramolecular Ester Transfer Reaction: Synthesis of a-Substituted g-Aminobutyric Acid (GABA) Derivatives, Org. Lett. 20024, 1499-1501. 

7. Akio Saito, Hisanaka Ito, and Takeo Taguchi, A stereoselective preparation of 1-fluorocyclopropane-1-carboxylate derivatives through radical addition of fluoroiodoacetate to alkenes followed by intramolecular substitution reaction, Tetrahedron 200157, 7487-7493.

6. Barry M. Trost, Elliad R Silcoff, and Hisanaka Ito, Direct Asymmetric Aldol Reactions of Acetone Using Bimetallic Zinc Catalysts, Org. Lett. 20013, 2497-2500.

5. Barry M. Trost, Hisanaka Ito, and Elliad R Silcoff, Asymmetric Aldol Reaction via a Dinuclear Zinc Catalyst. a-Hydroxyketones as Donors, J. Am. Chem. Soc. 2001123, 3367-3368. 

4. Barry M. Trost and Hisanaka Ito, A Direct Catalytic Enantioselective Aldol Reaction via a Novel Catalyst Design, J. Am. Chem. Soc. 2000122, 12003-12004. 

3. Azusa Sato, Hisanaka Ito, Yusuke Yamaguchi, and Takeo Taguchi, Cu(I)-Assisted carbon-carbon bond forming reactions of γ,γ-dialkoxyallylic zirconium species: A new versatile homoenolate equivalent of propionate, Tetrahedron Lett. 200041, 10239-10243.

2. Atsuro Nakazato, Toshihito Kumagai, Kazunari Sakagami, Ryoko Yoshikawa, Yoshiko Suzuki, Shigeyuki Chaki, Hisanaka Ito, Takeo Taguchi, Shigetada Nakanishi, and Shigeru Okuyama, Synthesis, SARs, and Pharmacological Characterization of 2-Amino-3 or 6-fluorobicyclo[3,1,0]hexane-2,6-dicarboxylic Acid Derivatives as Potent, Selective, and Orally Active Group II Metabotropic Glutamate Receptor Agonists, J. Med. Chem. 200043, 4893-4909.

1. Azusa Sato, Hisanaka Ito, and Takeo Taguchi, Reaction of γ,γ-Dialkoxyallylic Zirconium Species with Aldehyde As Protected Acryloyl Anion, J. Org. Chem. 200065, 918-921.