26) 縮環型天然物の全合成
大好孝幸，有機合成化学協会誌 2024, 82, 1184, DOI:10.5059/yukigoseikyokaishi.82.1184.
 
25) 天然物ハイブリッド化による『分子のり』の創出
大好孝幸, 木越英夫 有機合成化学協会誌 2024, 82, 483, DOI:10.5059/yukigoseikyokaishi.82.483.
 
24) Structure−Activity Relationship Studies on Scytophycin B, a Spiro Epoxide-Containing Cytotoxic Macrolide
T. Ohyoshi*, M. Namiki, S. Sato, I. Kikuchi, Y. Miyazaki, T. Noguchi, H. Kigoshi* Org. Lett. 2024, 26, 9996, DOI:10.1021/acs.orglett.4c03840
 
23) Total Synthesis of Aplysiasecosterols A and B, Two Marine 9,11-Secosteroids
T. Ohyoshi*, H. Iizumi, S. Hosono, H. Tano, H. Kigoshi* Org. Lett. 2023, 25, 4725, DOI:10.1021/acs.orglett.3c01692.
 
22) Discovery of New Cytotoxic Aplaminone Derivatives from the Sea Hare Aplysia kurodai and Elucidation of Their Accumulation from Local Sea Algae through the Food Chain
Y. Hioki, T. Sato, T. Iwao, J. Ikuma, A. Kawamura, T. Ohyoshi, Y. Tsunematsu, M. Kita* Eur. J. Org. Chem. 2023, 26, e202300084, DOI: 10.1002/ejoc.202300084.
 
21) Toward the Total Synthesis of Scytophycins: Synthesis of the C7-C21 Fragments of Scytophycins A, B, and C
T. Ohyoshi*, M. Namiki, Y. Miyazaki, S. Sato, T. Noguchi, H. Kigoshi* Tetrahedron Lett. 2023, 114, 154250, DOI: 10.1016/j.tetlet.2022.154250.
 
20) Isolation and Synthesis of Azuriaplysins A and B, Bromoditerpenes with an α-Methylene Carbonyl From the Sea Hare Aplysia kurodai
T. Ohyoshi*, Y. Zhao, H. Kigoshi* J. Nat. Prod. 2022, 85, 2082, DOI:10.1021/acs.jnatprod.2c00476.
 
19) Bioinspired Total Synthesis and Structure-Activity Relationship Studies on Aplaminal
T. Ohyoshi*, Y. Zhao, K. Akemoto, T. Ishihara, A. Taniguchi, M. Zhang, H. Kigoshi* Bull. Chem. Soc. Jpn. 2022, 95, 1242, DOI:10.1246/bcsj.20220149.
 
18) Total Synthesis of a PPAP, Nemorosonol, Using a Tandem Michael Addition–Intramolecular Aldol Reaction
K. Mitsugi, T. Takabayashi, T. Ohyoshi*, H. Kigoshi* Org. Lett. 2022, 24, 4635, DOI: 10.1021/acs.orglett.2c01745.
 
17) Structure–activity relationship studies on an antitumor marine macrolide using aplyronine A–swinholide A hybrid
T. Ohyoshi*, A. Takano, I. Kikuchi, T. Ogura, M. Namiki, Y. Miyazaki, T. Hirano, S. Konishi, Y. Ebihara, K. Takeno, I. Hayakawa, H. Kigoshi*, Org. Biomol. Chem. 2022, 20, 2922, DOI: 10.1039/D2OB00118G; *Highlighted in Synfacts, 2022 (18), 0797.
 
16) Recent Progress in Structure-Activity Relationship Studies on Antitumor Macrolide Aplyronine A by Using Hybridization of Actin-depolymerizing Natural Product
T. Ohyoshi*, H. Kigoshi* Chem. Lett. 2021, 50, 580, DOI:10.1246/cl.200866
 
15) Synthetic Studies toward Aplysiasecosterol A: Concise Synthesis of the Tricyclic Core and Its Reactions for Introduction of the D Ring Fragment
T. Ohyoshi*, H. Tano, H. Kigoshi Bull. Chem. Soc. Jpn. 2021, 94, 1179, DOI:10.1246/bcsj.20200401.
 
14) Total Synthesis and Structure–Activity Relationship Studies of Phelligridins C and D, and Phellifuropyranone A
T. Ohyoshi*, K. Mitsugi, F. Ichimura, T. Higuma, M. Yoshida, H. Kigoshi*, Bull. Chem. Soc. Jpn. 2020, 93, 1540, DOI:10.1246/bcsj.20200212.
 
13) Total synthesis of (–)-aplaminal by Buchwald-Hartwig cross-coupling of an aminal
T. Ohyoshi*, K. Akemoto, A. Taniguchi, T. Ishihara, H. Kigoshi* New J. Chem. 2019, 43, 18442, DOI:10.1039/C9NJ04743C.
 
12) Concise total syntheses of phelligridins A, C, and D
T. Ohyoshi*, K. Mitsugi, T. Higuma, F. Ichimura, M. Yoshida, H. Kigoshi* RSC Adv. 2019, 9, 7321, DOI:10.1039/C8RA10346A.
 
11) Synthetic studies toward swinhoeisterol A, a novel steroid with an unusual carbon skeleton
A. Takano, Y. Zhao, T. Ohyoshi, H. Kigoshi* Tetrahedron Lett. 2019, 60, 591, DOI:10.1016/j.tetlet.2019.01.027.
 
10) Development of a novel inducer of protein-protein interactions based on aplyronine A
T. Ohyoshi, A. Takano, M. Namiki, T. Ogura, Y. Miyazaki, Y. Ebihara, K. Takeno, I. Hayakawa*, H. Kigoshi* Chem. Commun. 2018, 54, 9537, DOI: 10.1039/C8CC04613A.
 
9) Total synthesis of biselide E, a marine polyketide
I. Hayakawa*, K. Suzuki, M. Okamura, S. Funakubo, Y. Onozaki, D. Kawamura, T. Ohyoshi, H. Kigoshi* Org. Lett. 2017, 19, 5713, DOI: 10.1021/acs.orglett.7b03009.
 
8) Total Synthesis of Biselide A, A Cytotoxic Macrolide of Marine Origin
I. Hayakawa*, M. Okamura, K. Suzuki, M. Shimanuki, K. Kimura, T. Yamada, T. Ohyoshi, H. Kigoshi* Synthesis, 2017, 49, 2958, DOI: 10.1055/s-0036-1588169.
 
7) Synthetic studies toward aplysiasecosterol A: Construction of the novel tricyclic core
T. Ohyoshi, H. Tano, K. Akemoto, H. Kigoshi* Tetrahedron Lett. 2017, 58, 3327, DOI:10.1016/j.tetlet.2017.07.036.
 
6) セコプレジザン型セスキテルペンJiadifenolideの全合成研究
大好孝幸 有機合成化学協会誌 2016, 74, 167, DOI:10.5059/yukigoseikyokaishi.74.167.
 
5) Total synthesis of natural derivative and artificial analogs of 13-oxyingenol and their biological evaluation
T. Ohyoshi, Y. Tamura, I. Hayakawa*, G. Hirai*, Y. Miyazawa, S. Funakubo, M. Sodeoka*, H. Kigoshi* Org. Biomol. Chem. 2016, 14, 11426, DOI: 10.1039/C6OB02268E.
 
4) Total Synthesis of (–)-13-Oxyingenol and its Natural Derivative
T. Ohyoshi, S. Funakubo, Y. Miyazawa, K. Niida, I. Hayakawa, H. Kigoshi* Angew. Chem. Int. Ed. 2012, 51, 4972, DOI: 10.1002/anie.201201383, *Highlighted in Synfacts 2012, 816.
 
3) Synthetic Studies Toward 13-Oxyingenol: Construction of the Fully Substituted Tetracyclic Compound
T. Ohyoshi, Y. Miyazawa, K. Aoki, S. Ohmura, Y. Asuma, I. Hayakawa, H. Kigoshi* Org. Lett. 2011, 13, 2160, DOI: 10.1021/ol103151k.
 
2) Synthetic studies toward optically active 13-oxyingenol via asymmetric cyclopropanation
I. Hayakawa, Y. Miyazawa, T. Ohyoshi, Y. Asuma, K. Aoki, H. Kigoshi* Synthesis, 2011, 5, 769, DOI: 10.1055/s-0030-1259430.
 
1) Synthetic study on 13-oxyingenol: construction of the full carbon framework
I. Hayakawa, Y. Asuma, T. Ohyoshi, K. Aoki, H. Kigoshi* Tetrahedron Lett. 2007, 48, 6221, DOI: 10.1016/j.tetlet.2007.06.135.
 
 
著書
２）　夢の糖をつくる
大好孝幸, 化学 (注目の論文), 化学同人, 2020-06, 60.
 
１）　天然物を基盤とした生体機能分子の創出
大好孝幸, 化学工業, 化学工業社, 2020-02, 107.