{"id":2118,"date":"2025-01-02T16:06:36","date_gmt":"2025-01-02T07:06:36","guid":{"rendered":"https:\/\/www.ls.toyaku.ac.jp\/~regenemed\/?page_id=2118"},"modified":"2025-07-24T22:05:04","modified_gmt":"2025-07-24T13:05:04","slug":"__trashed","status":"publish","type":"page","link":"https:\/\/www.ls.toyaku.ac.jp\/~regenemed\/__trashed\/","title":{"rendered":"\u8ad6\u6587\u767a\u8868"},"content":{"rendered":"\n

\u5b66\u8853\u8ad6\u6587\u30fb\u7dcf\u8aac<\/span><\/span>\u3000<\/h2>\n\n\n\n

2025\u5e74<\/h3>\n\n\n\n

Oikawa M<\/strong>#<\/sup>, Kojima H<\/strong>#<\/sup>, Kobayashi H, Iwatsuki K, Saito H, Sanbo M, Nishioka K, Yamaguchi T<\/strong>, Yamamoto T, Kurimoto K, Hirabayashi M, Kobayashi T. Transcription factor-mediated germ cell induction in rats reveals ETV4 cooperates with germline specifiers. Stem Cell Rep<\/em>., accepted. (2025) #: contributed equally.<\/p>\n\n\n\n

Francois–Campion V, Berger F, Oikawa M<\/strong>, Goumeidane M, Mouni\u00e9e N, Chenouard V, Petrova K, Abreu JG, Fourgeux C, Poschmann J, Peshkin L, Gibeaux R, Jullien J. Sperm derived H2AK119ub1 is required for embryonic development in Xenopus laevis<\/em>. Nature Commun<\/em>., volume 16, Article number: 3268. (2025)<\/p>\n\n\n\n

Shiiba I, Ito N, Oshio H, Ishikawa Y, Nagao T, Shimura H<\/strong>, Oh KW, Takasaki E, Yamaguchi F, Konagaya R, Kadowaki H, Nishitoh H, Tanzawa T, Nagashima S<\/strong>, Sugiura A, Fujikawa Y, Umezawa K, Tamura Y, Il Lee B, Hirabayashi Y, Okazaki Y, Sawa T, Inatome R, Yanagi S. ER-mitochondria contacts mediate lipid radical transfer via RMDN3\/PTPIP51 phosphorylation to reduce mitochondrial oxidative stress. Nat Commun., <\/em>16(1):1508. doi: 10.1038\/s41467-025-56666-4. (2025)<\/p>\n\n\n\n

Tanabe M, Saito Y, Takasaki A, Nakano K<\/strong>, Yamamoto S<\/strong>, Suzuki C, Kawamura N, Hattori A, Oikawa M<\/strong>, Nagashima S<\/strong>, Yanagi S, Yamaguchi T<\/strong>, Fukuda T<\/strong>*. Role of immature choroid plexus in the pathology of model mice and human iPSC-derived organoids with autism spectrum disorder. Cell Rep<\/em>. 44, 115133, doi: 10.1016\/j.celrep.2024.(2025)
\u798f\u7530\u8b1b\u5e2b\u30b0\u30eb\u30fc\u30d7\u304c\u3001\u672a\u6210\u719f\u306a\u8108\u7d61\u53e2\u304c\u81ea\u9589\u75c7\u306e\u65b0\u305f\u306a\u6cbb\u7642\u6a19\u7684\u3068\u306a\u308b\u3053\u3068\u3092\u660e\u3089\u304b\u306b\u3057\u307e\u3057\u305f\uff01<\/strong>\u3000<\/span>
\u203b\u304a\u540d\u524d\u304c\u592a\u5b57\u306e\u65b9\u306f\u30012025\u5e741\u6708\u73fe\u5728\u306e\u7814\u7a76\u5ba4\u5728\u7c4d\u30e1\u30f3\u30d0\u30fc\u3067\u3059\u3002
\u2003\u30d7\u30ec\u30b9\u30ea\u30ea\u30fc\u30b9\u8cc7\u6599\uff08\u6771\u4eac\u85ac\u79d1\u5927\u5b66\uff09<\/a><\/span>\u3000<\/a>\u3000 \u6771\u4eac\u85ac\u79d1\u5927\u5b66 \u7814\u7a76\u30dd\u30fc\u30bf\u30eb<\/a><\/span>\u3000<\/a>\u2003<\/span>Cell Reports website<\/a>\u3000<\/p>\n\n\n\n

2024\u5e74<\/h3>\n\n\n\n

Shimura H<\/strong>, Yamamoto S<\/strong>, Shiiba I, Oikawa M<\/strong>, Uchinomiya S, Ojida A, Yanagi S, Kadowaki H, Nishitoh H, Fukuda T<\/strong>, Nagashima S*, Yamaguchi T<\/strong>*. Etomoxir suppresses the expression of PPARgamma2 and inhibits the thermogenic gene induction of brown adipocytes through pathways other than \u03b2-oxidation inhibition. J Biochem<\/em>.  2024 Dec 27. doi: 10.1093\/jb\/mvae092.
\u2003 <\/span>The Journal of Biochemistry website<\/a>\u3000<\/p>\n\n\n\n

Oi A, Shinoda N, Nagashima S<\/strong>, Miura M, Obata F. A nonsecretory antimicrobial peptide mediates inflammatory organ damage in Drosophila renal tubules. Cell Rep. <\/em>doi: 10.1016\/j.celrep.2024.115082. (2024)<\/p>\n\n\n\n

Francois-Campion V, Berger F, Oikawa M<\/strong>, Goumeidane M, Gibeaux R, Jullien J. Sperm derived H2AK119ub1 is required for embryonic development in Xenopus Laevis. bioRxiv.<\/em> 2024.04.23.590676. doi: https:\/\/doi.org\/10.1101\/2024.04.23.590676v1 (2024)<\/p>\n\n\n\n

Oikawa M<\/strong>, Hirabayashi M, Kobayashi T. Induction of Primordial Germ Cell-Like Cells from Rat Pluripotent Stem Cells. Methods Mol Biol.<\/em> 2024;2770:99-111. (2024)<\/p>\n\n\n\n

Kinoshita S, Ishii M, Ando J, Kimura T, Yamaguchi T<\/strong>, Harada S, Takahashi F, Nakashima K, Nakazawa Y, Yamazaki S, Ohshima K, Takahashi K, Nakauchi H, Ando M. Rejuvenated iPSC-derived GD2-directed CART Cells Harbor Robust Cytotoxicity Against Small Cell Lung Cancer. Cancer Res Commun<\/em>., 4(3):723-737. 8(2024)<\/p>\n\n\n\n

2023\u5e74<\/h3>\n\n\n\n

Takeuchi K, Tabe S, Takahashi K, Aoshima K, Matsuo M, Ueno Y, Furukawa Y, Yamaguchi K, Ohtsuka M, Morinaga S, Miyagi Y, Yamaguchi T<\/strong>, Tanimizu N,Taniguchi H. Incorporation of human iPSC-derived stromal cells creates a pancreatic cancer organoid with heterogeneous cancer-associated fibroblasts. Cell Rep.<\/em>, 42(11):113420. (2023)<\/p>\n\n\n\n

Iwatsuki K, Oikawa M,<\/strong> Kobayashi H, Penfold CA, Sanbo M, Yamamoto T, Hochi S, Kurimoto K, Hirabayashi M, Kobayashi T. Rat post-implantation epiblast-derived pluripotent stem cells produce functional germ cells. Cell Rep Methods.<\/em> 3(8):100542. (2023)<\/p>\n\n\n\n

Kano M, Mizuno N, Sato H, Kimura T, Hirochika R, Iwasaki Y, Inoshita N, Nagano H, Kasai M, Yamamoto H, Yamaguchi T, <\/strong>Suga H, Masaki H, Mizutani E, Nakauchi H. Functional calcium-responsive parathyroid glands generated using single-step blastocyst complementation. Proc Natl Acad Sci U S A<\/em>.,120(28):e2216564120. (2023)<\/p>\n\n\n\n

Richard Albert J, Kobayashi T, Inoue A, Monteagudo-S\u00e1nchez A, Kumamoto S, Takashima T, Miura A, Oikawa M<\/strong>, Miura F, Takada S, Hirabayashi M, Korthauer K, Kurimoto K, Greenberg MVC, Lorincz M, Kobayashi H. Conservation and divergence of canonical and non-canonical imprinting in murids. Genome Biol.<\/em>, 24(1):48. (2023)<\/p>\n\n\n\n

Zecchini V, Paupe V, Herranz-Montoya I, Janssen J, Wortel IMN, Morris JL, Ferguson A, Roy Chowdury S, Segarra-Mondejar M, Costa ASH, Pereira GC, Tronci L, Young T, Nikitopoulou T, Yang M, Bihary D, Caicci F, Nagashima S<\/strong>, Speed A., Bokea K., Baig Z., Samarajiwah S., Tran M., Mitchell T., Johnson M,Prudent J, Frezza C. Fumarate induces vesicular release of mtDNA to drive innate immunity. Nature<\/em>, 615(7952):499-506. (2023)<\/p>\n\n\n\n

Tsuzuki S, Yamaguchi T,<\/strong> Okumura T, Kasai T, Taniguchi H. PDGF Receptors and Signaling Are Required for 3D-Structure Formation and Differentiation of Human iPSC-Derived Hepatic Spheroids. Int.J.Mol.Sci.<\/em>,24(8),7075. (2023)<\/p>\n\n\n\n

2022\u5e74<\/h3>\n\n\n\n

Tokuyama T, Uosaki H, Sugiura A, Nishitai G, Takeda K, Nagashima S,<\/strong> Shiiba I, Ito N, Amo T, Mohri S, Nishimura A, Nishida M, Konno A, Hirai H, Ishido S, Yoshizawa T, Shindo T, Takada S, Kinugawa S, Inatome R, Yanagi S. Protective roles of MITOL against myocardial senescence and ischemic injury partly via Drp1 regulation. iScience<\/em>, 25(7):104582. (2022)<\/p>\n\n\n\n

Nagashima S<\/strong>, Ito N, Shiiba I, Shimura H<\/strong>, Yanagi S. Ubiquitin-mediated mitochondrial regulation by MITOL\/MARCHF5 at a glance. J Biochem. 27;173(1):1-11 (2022)<\/p>\n\n\n\n

Ito N, Takahashi T., Shiiba I., Nagashima S<\/strong>., Inatome R., Yanagi S. MITOL regulates phosphatidic acid-binding activity of RMDN3\/PTPIP51. J Biochem.<\/em> 2022. 171(5):529-541<\/p>\n\n\n\n

Okuda R, Gjeta B, Popovic D, Maynard A, Yu Q, He Z, Santel M, Seimiya M, Morinaga S, Miyagi Y, Yamaguchi T,<\/strong> Ueno Y, Taniguichi H, Treutlein B, Camp J.G. Reconstructing cell interactions and state trajectories in pancreatic cancer stromal tumoroids. bioRxiv<\/em> doi: https:\/\/doi.org 10.1101\/2022.02.14.480334. (2022)<\/p>\n\n\n\n

Yamazaki K, Kubara K, Ishii S, Li P, Dairiki R, Hihara T, Ishizuka Y, Izumi Y, Kumai M, Kamisako T, Ishizaki H, Sato H, Masaki H, Mizuno N, Mitsuhashi K, Ito M, Hamanaka S, Yamaguchi T,<\/strong> Watanabe M, Sugiyama F, Nakauchi H. In vitro and in vivo functions of T cells produced in complemented thymi of chimeric mice generated by blastocyst complementation. Sci Rep. <\/em>2022.12(1):3242. (2022)<\/p>\n\n\n\n

\u5fd7\u6751\u5ba5\u54c9, \u9577\u5cf6\u99ff<\/strong>. \u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u3092\u4ecb\u3057\u305f\u30aa\u30eb\u30ac\u30cd\u30e9\u306e\u9023\u643a, Journal of Japanese Biochemical Society 94(2): 170-179 (2022)<\/p>\n","protected":false},"excerpt":{"rendered":"

\u5b66\u8853\u8ad6\u6587\u30fb\u7dcf\u8aac\u3000 2025\u5e74 Oikawa M#, Kojima H#, Kobayashi H, Iwatsuki K, Saito H, Sanbo M, Nishioka K, Yamaguchi T, Yamam […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"swell_btn_cv_data":"","footnotes":""},"class_list":["post-2118","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/www.ls.toyaku.ac.jp\/~regenemed\/wp-json\/wp\/v2\/pages\/2118"}],"collection":[{"href":"https:\/\/www.ls.toyaku.ac.jp\/~regenemed\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.ls.toyaku.ac.jp\/~regenemed\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.ls.toyaku.ac.jp\/~regenemed\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.ls.toyaku.ac.jp\/~regenemed\/wp-json\/wp\/v2\/comments?post=2118"}],"version-history":[{"count":15,"href":"https:\/\/www.ls.toyaku.ac.jp\/~regenemed\/wp-json\/wp\/v2\/pages\/2118\/revisions"}],"predecessor-version":[{"id":2545,"href":"https:\/\/www.ls.toyaku.ac.jp\/~regenemed\/wp-json\/wp\/v2\/pages\/2118\/revisions\/2545"}],"wp:attachment":[{"href":"https:\/\/www.ls.toyaku.ac.jp\/~regenemed\/wp-json\/wp\/v2\/media?parent=2118"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}