Publication

発表論文
２００８年

Farhan, H., Weiss, M., Tani, K., Kaufman, R. J., and Hauri, H. P. Adaptation of endoplasmic
reticulum exit sites to acute and chronic increases in cargo load. EMBO J. in press (2008)

Inoue, M., Arasaki, K., Ueda, A., Aoki, T., and Tagaya, M. N-terminal region of ZW10 serves
not only as a determinant for localization but also as a link with dynein function. Genes Cells 13:
905-914 (2008)

Wakana, Y., Takai, S., Nakajima, K., Tani, K., Yamamoto, A., Watson, P., Stephens, D., Hauri,
H.-P., and Tagaya, M. Bap31 is an itinerant protein that moves between the peripheral ER and a
juxtanuclear compartment related to ER-associated degradation. Mol. Biol. Cell 19: 1825-1836
(2008)

Aoki, T., Kojima, M., Tani, K., and Tagaya, M. Sec22b-dependent assembly of endoplasmic
reticulum Q-SNARE proteins. Biochem. J. 410: 93-100 (2008)

２００７年

Ballar, P., Zhong, Y., Nagahama, M., Tagaya, M., Shen, Y., and Fang, S. (2007) Identification of
SVIP as an endogenous inhibitor of endoplasmic reticulum-associated degradation. J. Biol. Chem.
282: 33908-33914 (2007)
Arasaki, K., Uemura, T., Tani, K., and Tagaya, M. Correlation of Golgi localization of ZW10 and
centrosomal accumulation of dynactin. Biochem. Biophys. Res. Commun. 359: 811-816 (2007)
Iinuma, T., Shiga, A., Nakamoto, K., O'brien, M. B., Aridor ,M., Arimitsu, N., Tagaya, M., and
Tani, K. Mammalian Sec16/p250 plays a role in membrane traffic from the endoplasmic reticulum.
J. Biol. Chem. 282: 17632-17639 (2007)
Arasaki, K., Tani, K., Yoshimori, T., Stephens, D. J., and Tagaya, M. Nordihydroguaiaretic acid
affects multiple dynein-dynactin functions in interphase and mitotic cells. Mol. Pharmacol. 71:
454-460 (2007)

２００６年

Yamasaki, A., Tani, K., Yamamoto, A., Kitamura, N., and Komada, M. The Ca2+-binding protein
ALG-2 is recruited to endoplasmic reticulum exit sites by Sec31A and stabilizes the localization
of Sec31A. Mol. Biol. Cell 17: 4876-4887 (2006)
Nagahama, M., Yamazoe, T., Hara, Y., Tani, K., Tsuji, A., and Tagaya, M. The AAA-ATPase NVL2
is a component of pre-ribosomal particles that interacts with the DExD/H-box RNA helicase DOB1.
Biochem. Biophys. Res. Commun. 346: 1075-1082 (2006)
Arasaki, K., Taniguchi, M., Tani, K., and Tagaya, M. RINT-1 regulates the localization and entry
of ZW10 to the syntaxin 18 complex. Mol. Biol. Cell 17: 2780-2788 (2006)
Kitami, M. I., Kitami, T., Nagahama, M., Tagaya, M., Hori, S., Kakizuka, A., Mizuno, Y., and Hattori, N.
Dominant-negative effect of mutant valosin-containing protein in aggresome formation.
FEBS Lett. 580: 474-478 (2006)
Hirao, N., Sato, S., Gotoh, T., Maruoka, M., Suzuki, J., Matsuda, S., Shishido, T., and Tani, K.
NESH (Abi-3) is present in the Abi/WAVE complex but does not promote c-Abl-mediated
phosphorylation. FEBS Lett. 580: 464-470 (2006)

２００5年

Wakana, Y., Koyama, S., Nakajima, K., Hatsuzawa, K., Nagahama, M., Tani, K., Hauri, H.-P.,
Melancon, P., and Tagaya, M. Reticulon 3 is involved in membrane trafficking between the
endoplasmic reticulum and Golgi. Biochem. Biophys. Res. Commun. 334: 1198-1205 (2005)
Maruoka, M., Suzuki, J., Kawata, S., Yoshida, K., Hirao, N., Sato, S., Goff, S. P., Takeya, T., Tani,
K., and Shishido, T. Identification of B cell adaptor for PI3-kinase (BCAP) as an Abl interactor 1-
regulated substrate of Abl kinases. FEBS Lett. 579: 2986-2990 (2005)
Bossis, I., Roden, R. B. S., Gambhira, R., Yang, R., Tagaya, M., Howley, P. M., and Meneses, P. I.
Interaction of tSNARE Syntaxin 18 with the papillomavirus minor capsid protein mediates
infection. J. Virol. 79: 6723-6731 (2005)
Kops, G. J., Kim, Y., Weaver, B. A., Mao, Y., McLeod, I., Yates, J. R. 3rd, Tagaya, M., and Cleveland,
D. W. ZW10 links mitotic checkpoint signaling to the structural kinetochore. J. Cell Biol. 169:
49-60 (2005)
Shimoi, W., Ezawa, I., Nakamoto, K., Uesaki, S., Gabreski, G., Aridor, M., Yamamoto, A., Nagahama,
M., Tagaya, M., and Tani, K. p125 is localized in endoplasmic reticulum exit sites and involved
in their organization. J. Biol. Chem. 280: 10141-10148 (2005)

２００4年

Nagahama, M., Hara, Y., Seki, A., Yamazoe, T., Kawate, Y., Shinohara, T., Hatsuzawa, K., Tani,
K., and Tagaya, M. NVL2 is a nucleolar AAA-ATPase that interacts with ribosomal protein
L5 through its nucleolar localization sequence. Mol. Biol. Cell 15: 5712-5723 (2004)
Nakajima, K., Hirose, H., Taniguchi, M., Kurashina, H., Arasaki, K., Nagahama, M., Tani, K.,
Yamamoto, A., and Tagaya, M. Involvement of BNIP1 in apoptosis and endoplasmic reticulum
membrane fusion. EMBO J. 23: 3216-3226 (2004)
Hirose, H., Arasaki, K., Dohmae, N., Takio, K., Hatsuzawa, K., Nagahama, M., Tani, K., Yamamoto,
A., Tohyama, M., and Tagaya, M. Implication of ZW10 in membrane trafficking between the
endoplasmic reticulum and Golgi. EMBO J. 23: 1267-1278 (2004)

２００３年

Vikman, J., Ma, X., Tagaya, M., and Eliasson L. Requirement for N-ethylmaleimide-sensitive factor
for exocytosis of insulin-containing secretory granules in pancreatic beta-cells. Biochem. Soc.
Trans. 31: 842-847 (2003)
Kawase, K., Shibata, M., Kawashima, H., Hatsuzawa, K., Nagahama, M., Tagaya, M., and Tani, K.
Gaf-1b is an alternative splice variant of Gaf-1/Rip11. Biochem. Biophys. Res. Commun. 303:
1042-046 (2003)
Tani, K., Shibata, M., Kawase, K., Kawashima, H., Hatsuzawa, K., Nagahama, M., and Tagaya, M.
Mapping of functional domains of gamma-SNAP. J. Biol. Chem. 278: 13531-13538 (2003)
Tani, K., Sato, S., Sukezane, T., Kojima1, H., Hirose, H., Hanafusa, H., and Shishido, T. Abl
interactor 1 promotes tyrosine 296 phosphorylation of mammalian Enabled (Mena) by c-Abl
kinase. J. Biol. Chem. 278: 1685-1692 (2003)
Nagahama, M., Suzuki, M., Hamada, Y., Hatsuzawa, K., Tani, T., Yamamoto, A., and Tagaya, M.
SVIP is a novel VCP/p97-interacting protein whose expression causes cell vacuolation. Mol. Biol.
Cell 14: 262-273 (2003)

２００２年

Nakajima, K., Sonoda, H., Mizoguchi, T., Aoki, J., Arai, H., Nagahama, M., Tagaya, M., and Tani, K.
A novel phospholipase A1 with sequence homology to a mammalian Sec23p-interacting protein,
p125. J. Biol. Chem. 277: 11329-11335 (2002)
Nagahama, M., Usui, S., Shinohara, T., Yamaguchi, T., Tani, K., and Tagaya, M. Inactivation of
Gαz causes disassembly of the Golgi apparatus. J. Cell Sci. 115: 4483-4493(2002)

２００１年

Kuroiwa, N., Nakamura, M., Tagaya, M., and Takatsuki, A. (2001) Arachidonyltrifluoromethy
ketone, a phospholipase A2 antagonist, induces dispersal of both Golgi stack-and trans Golgi
network-resident proteins throughout the cytoplasm. Biochem Biophys Res Commun. 281: 582-
588
Kubota, T., Ito, Y., Sekimizu, K., Tagaya, M., and Katayama, T. DnaA protein Lys-415 is close
to the ATP-binding site: ATP-pyridoxal affinity labeling. Biochem. Biophys. Res. Commun.
288: 1141-1148 (2001)

２０００年

Yamaguchi, T., Nagahama, M., Itoh, H., Hatsuzawa, K., Tani, K., and Tagaya, M. Regulation of the
Golgi structure by the α-subunits of heterotrimeric G proteins. FEBS Lett.470: 25-28 (2000)
Hatsuzawa, K., Hirose, H., Tani, K., Yamamoto, A. Scheller, R.H., and Tagaya, M. Syntaxin18:
a SNARE that functions in the endoplasmic reticulum, intermediate compartment, and cis-Golgi
vesicle trafficking. J. Biol. Chem. 275: 13713-13720 (2000)
Kano, F., Sako, Y., Tagaya, M., Yanagida, T., and Murata, M. Reconstitution of brefeldin A-induced
Golgi tubulation and fusion with the endoplasmic reticulum in semi-intact Chinese hamster ovary
cells. Mol. Biol. Cell 11: 3073-3087 (2000)
Mashima, J., Nagahama, M., Hatsuzawa, K., Tani, K., Horigome, T., Yamamoto, A., and Tagaya, M.
N-Ethylmaleimide-sensitive factor (NSF) is associated with the nuclear envelope. Biochem. Biophys.
Res. Commun. 274: 559-564 (2000)
Fukunaga, T., Nagahama, M., Hatsuzawa, K., Tani, K., Yamamoto, A., and Tagaya, M. Implication
of sphingolipid metabolism in the stability of the Golgi apparatus. J. Cell Sci. 113: 3299-3307 (2000)
Mizoguchi, T., Nakajima, K., Hatsuzawa, K., Nagahama, M., Hauri, H.-P., Tagaya, M., and Tani, K.
Determination of Functional Regions of p125, a Novel Mammalian Sec23p-Interacting Protein.
Biochem. Biophys. Res. Commun. 279: 144-149 (2000)

１９９９年

Tani, K., Oyama, Y., Hatsuzawa, K., and Tagaya, M. Hypothetical Protein KIAA0079 is a mammalian
homologue of yeast Sec24p. FEBS Lett.447:247-250 (1999)
Tani, K., Mizoguchi, T., Iwamatsu, A., Hatsuzawa, K., and Tagaya, M., p125 is a novel mammalian
Sec23p-interacting protein with structural similarity to phospholipid-modifying proteins. J. Biol.
Chem. 274: 20505-20512 (1999)

１９９８年

Mori, H., Sugiyama, H., Yamanaka, M., Sato, K., Tagaya, M., and Mizushima, S. Amino-terminal
region of SecA is involved in the function of SecG for protein translocation into Escherichia coli
membrane vesicles. J. Biochem. 124: 122-129 (1998)
Nishimune, A., Isaac, J. T. R., Molnar, E., Noel, J., Nash, S. R., Tagaya, M., Collingridge, G. L.,
Nakanishi, S.,and Henley, J. M. NSF binding to GluR2 regulates synaptic transmission. Neuron
21: 87-97 (1998)
Fukunaga, T., Furuno, A., Hatsuzawa, K., Tani, K., Yamamoto, A., and Tagaya, M., NSF is required
for the brefeldin A-promoted disassembly of the Golgi apparatus. FEBS Lett. 435: 237-240
(1998)
Yamaguchi, T., Nakayama, K., Hatsuzawa, K., Tani, K., Himeno, M., and Tagaya, M., ADP-
ribosylation factor-1 is sensitive to N-ethylmaleimide. J. Biochem. 124: 1229-1236
(1998)

１９９７年

Hatsuzawa, K., Tagaya, M., and Mizushima, S.The hydrophobic region of signal peptides is a
determinant for SRP recognition and protein translocation across the ER membrane. J. Biochem.
121: 111-118 (1997)
Igarashi, M., Tagaya, M., and Komiya, Y. The soluble N-ethylmaleimide-sensitive factor attached
protein receptor complex in growth cones: molecular aspects of the axon terminal development.
J Neurosci. 17: 1740-1750 (1997)
Sato, K., Mori, H., Yoshida, M., Tagaya, M., and Mizushima, S. Short hydrophobic segments in
the mature domain of proOmpA determine its stepwise movement during translocation across
the cytoplasmic membrane of Escherichia coli. J. Biol. Chem. 272: 5880-5886 (1997)
Takuma,T., Tagaya, M., and Ichida, T. Evidence for the putative docking/fusion complex of exocytosis
in parotid acinar cells. FEBS Lett. 404: 34-36 (1997)
Mori, H., Araki, M., Hikita, C., Tagaya, M., and S. Mizushima. The hydrophobic region of signal peptides
is involved in the interaction with membrane bound SecA. Biochim. Biophys. Acta 1326: 23-36
(1997)
Sato, K., Mori, H., Yoshida, M., Tagaya, M., and Mizushima, S. In vitro analysis of the
stop-transfer process during translocation across the cytoplasmic membrane of Escherichia coli .
J. Biol. Chem. 272: 20082-20087 (1997)
Yamaguchi, T., Yamamoto, A., Furuno, A., Hatsuzawa, K., Tani, K., Himeno, M., and Tagaya, M.
Possible involvment of heterotrimeric G proteins in the organization of the Golgi apparatuts.
J. Biol. Chem. 272: 25260-25266

１９９６年

Steel, G. J., Tagaya, M., and Woodman, P. G. Association of the fusion protein NSF with clathrin-
coated vesicle membranes. EMBO J. 15: 745-752 (1996)
Tagaya, M., Furuno, A., and Mizushima, S. SNAP prevents Mg2+-ATP-induced release of NSF from
the Golgi apparatus in digitonin-permeabilized PC 12 cells. J. Biol. Chem. 271: 466-470 (1996)
Tagaya, M., Henomatsu, N., Yoshimori, T., Yamamoto, A., Tashiro, Y., and Mizushima, S. Inhibition
of vesicle-mediated protein transport by nordihydroguaiaretic acid. J. Biochem. 119: 863-869 (1996)
Boudier, J. -A., Charvin, N., Boudier, J.-L., Fathallah, M., Tagaya, M., Takahashi, M., Seager, M. J.
Distribution of components of the SNARE complex in relation to transmitter release sites at the frog
neuromuscular junction. Eur. J. Neurosci. 8: 545-552 (1996)
Sato, K., Mori, H., Yoshida, M., and Mizushima, S. Characterization of a potential catalytic reside,
Asp-133 in the high affinity ATP-binding site of Escherichia coli SecA, translocation ATPase. J. Biol.
Chem. 271:17439-17444 (1996)
Tagaya, M., Genma, T., Yamamoto, A., Kozaki, S., and Mizushima, S. SNAP-25 is present on
chromaffin granules and acts as a SNAP receptor. FEBS Lett. 394, 83-86 (1996)

１９９５年

Matsuyama, S. and Mizushima, S. Biochemical analyses of components comprising the protein
translocation machinery of Eschericha coli. Cell. Mol. Biol. 4: 61-74 (1995)
Breukink, E., Nouwen, N., van Raalte, A., Mizushima, S., Tommassen, J., and de Kruijiff, B.
The C-terminus of SecA is involved in both lipid binding and SecB binding. J. Biol. Chem. 270:
7902-7907 (1995)
Ikonen, E., Tagaya, M., Ullrich, O., Montecucco, C., and Simons, K. Different requirement for
NSF and SNAP in apical and basolateral transport in MDCK cells. Cell 81: 571-580 (1995)
Moriyama, Y., Yamamoto, A., Tagaya, M., Tashiro, Y., and Michibata, H. Localization of
N-ethylmaleimide-sensitive fusion protein. NeuroRep. 6: 1757-1760 (1995)
Tagaya, M., Toyonaga, S., Takahashi, M., Yamamoto, A., Fujiwara, T., Akagawa, K., Moriyama, Y.,
and Mizushima, S. Syntaxin 1 (HPC-1) is associated with chromaffin granules. J. Biol. Chem. 270:
15930-15933 (1995)
Nishiyama, K., Mizushima, S., and Tokua, H. Preferential interaction of SecG with SecE
stabilizes an unstabile SecE-derivative in the Escherichia coli cytoplasmic membrane. Biochem.
Biophys. Res. Commun. 217: 217-223 (1995)
Uchida, K., Mori, H., and Mizushima, S. Stepwise movement of preproteins in the process of
translocation across the cytoplasmic membrane of Escherichia coli. J. Biol. Chem. 270:
30862-30868 (1995)