Satoshi Akanuma

Tokyo University of Pharmacy and Life Sciences, Assistant Professor, Ph.D.

Office

Tokyo University of Pharmacy and Life Sciences
Department of Molecular Biology
Horinouchi, Hachioji, Tokyo, 192-0392, Japan
Phone: +81-426-76-7139
Fax: +81-426-76-7145
E-mail: akanuma@ls.toyaku.ac.jp
(When you send e-mail by PC software, please add "ls.toyaku.ac.jp" after "@")

1998 Ph. D. in Science at Tokyo Institute of Technology (Japan)

1998-2001 Special Post Doctoral Researcher at RIKEN Institute (Japan)

2001 Research Associate at RIKEN Genomic Sciences Center (Japan)

2001-2003 Alexander von Humboldt Foundation Post Doctoral Researcher at Cologne University (Germany)

2003-2005 Post Doctoral Researcher at JST BIRD (Japan)

2005-2006 Post Doctoral Researcher at NFRI (Japan)

2006- Assistant Professor at Tokyo University of Pharmacy and Life Sciences (Japan)

Random mutagenesis improves the low-temperature activity of the tetrameric 3-isopropylmalate dehydrogenase from the hyperthermophile Sulfolobus tokodaii.
Sasaki M, Uno M, Akanuma S, Yamagishi A. (2008) Protein Eng Des Sel 21:721-727
Experimental evidence for the existence of a stable half-barrel subdomain in the (beta/alpha)8-barrel fold.
Akanuma S, Yamagishi A. (2008) J Mol Biol 382:458-466
Identification and characterization of key substructures involved in the early folding events of a (beta/alpha)8-barrel protein as studied by experimental and computational methods.
Akanuma S, Yamagishi A. (2005) J Mol Biol 353:1161-1170
A detailed unfolding pathway of a (beta/alpha)8-barrel protein as studied by molecular dynamics simulations.
Akanuma S, Miyagawa H, Kitamura H, Yamagishi A. (2005) Proteins: Structure, Function, and Bioinformatics 58:538-546
Combinatorial mutagenesis to restrict amino acid usage in an enzyme to a reduced set.
Akanuma S, Kigawa T, Yokoyama S. (2002) Proc Natl Acad Sci USA 99:13549-13553