92. Toyoharu Kobayashi, Futaba Hayano, Akinobu Kamiya, Yuichiro Kawamoto, and Hisanaka Ito, Asymmetric Total Synthesis of (+)-Lemnardosinane A, submitted.
91. Yuichiro Kawamoto, Shin-ichiro Yomura, Toyoharu Kobayashi, and Hisanaka Ito, Synthetic Study of Leptosperol A, submitted.
90. Hideki Abe, Nanako Inaba, Mayu Nomura, Yuta Ogura, Naoki Fukazawa, Ryohei Saito-Moriya, Yuichiro Kawamoto, Toyoharu Kobayashi, and Hisanaka Ito, Total synthesis of (±)-paralemnolin A, Tetrahedron Lett.2024, 139, 154991.
89. Toyoharu Kobayashi, Rina Sugitate, Kyohei Uchida, Yuichiro Kawamoto, and Hisanaka Ito, Asymmetric Total Synthesis of Lemnalemnane A, Org. Lett.2024, 26, 1803-1806.
88. Yuichiro Kawamoto and Hisanaka Ito, Total Synthesis of Ganoderma Meroterpenoids - Progresses since 2014, Asian J. Org. Chem. in press.
86. Yuichiro Kawamoto, Ayaka Nishitani, Yukari Yoshimura, Toyoharu Kobayashi, and Hisanaka Ito, Total Synthesis of Phomopsol B, Chem. Commun. 2024, 60, 95-97.
85. Toyoharu Kobayashi, Yuya Teshigahara, Momoyo Sakakibara, Kazuya Murakami, Yuichiro Kawamoto, and Hisanaka Ito, Total Synthesis Asperaculin A, Org. Lett.2023, 25, 4510-4513.
84. Kyohei Uchida, Yuichiro Kawamoto, Toyoharu Kobayashi, and Hisanaka Ito, Total Synthesis of Applanatumol A, Chem. Commun.2023, 59, 8139-8142.
83. Yuichiro Kawamoto, Naoki Noguchi, Toyoharu Kobayashi, and Hisanaka Ito, Total synthesis of lucidumone througu convenient one-pot preparation of the tetracyclic skeleton by Claisen rearrangement and subsequent intramolecular aldol reaction, Angew. Chem. Int. Ed.2023, 62, e202304132. Hot Paper
82. Yuichiro Kawamoto, Shin-ichiro Yomura, Fuka Karube, Toyoharu Kobayashi, and Hisanaka Ito, The first total synthesis of Leptosperol B through stereocontrolled intramolecular 1,4-addition to construct octahydronaphthalene framework, J. Org. Chem.2023, 88, 3217-3227.
80. Yuichiro Kawamoto, Toyoharu Kobayashi, and Hisanaka Ito, Total synthesis of halogenated spirocyclic polyketide (±)-actinospirol A, Tetrahedron Lett.2022, 103, 153975.
79. Akinobu Kamiya, Yuichiro Kawamoto, Toyoharu Kobayashi, and Hisanaka Ito, Asymmetric Syntheses of ent-Callilongisins B and C, Tetrahedron2022, 111, 132712.
78. Yuichiro Kawamoto, Toyoharu Kobayashi, and Hisanaka Ito, Asymmetric Total Synthesis of Stachyodins A and B, Tetrahedron2022, 106-107, 132595.
77. Yuichiro Kawamoto, Naoki Noguchi, Daiki Ozone, Toyoharu Kobayashi, and Hisanaka Ito, Convenient preparation of synthetically useful chiral quaternary carbon-containing bicyclic compounds with organocatalysts, Tetrahedron Lett.2021, 85, 153495.
76. Takeshi Yamamotoya, Yusuke Nakatsu, Shun Hasei, Yukino Ohata, Jeffrey Encinas, Hisanaka Ito, Takayoshi Okabe, Tomoichiro Asano, and Takemasa Sakaguchi, Prolyl isomerase Pin1 plays an essential role in SARS-CoV-2 proliferation, implicating the possibility as a novel therapeutic target, Sci. Rep.2021, 11, 18581.
75. Yuichiro Kawamoto, Hideki Kitsukawa, Toyoharu Kobayashi, and Hisanaka Ito, Total Synthesis of Nesteretal A, Org. Lett.2021, 23, 7074-7078.
73. Yasuka Matsunaga, Shun Hasei, Takeshi Yamamotoya, Hiroaki Honda, Akifumi Kushiyama, Hideyuki Sakoda, Midori Fujishiro, Hikaru Ono, Hisanaka Ito, Takayoshi Okabe, Tomoichiro Asano, and Yusuke Nakatsu, Pathological role of Pin1 in the development of DSS-induced colitis, Cells2021, 10, 1230.
72. Yuichiro Kawamoto, Toyoharu Kobayashi, and Hisanaka Ito, Total Synthesis of Stachyodin A via One-Pot Suzuki Coupling for Quick Construction of Carbon Skeleton, Org. Lett.2021, 23, 3864-3867.
71. Yuichiro Kawamoto, Fuka Karube, Toyoharu Kobayashi, and Hisanaka Ito, Stereocontrolled Asymmetric Synthesis of Mollebenzylanols A and B Using Claisen Rearrangements, Tetrahedron2021, 83, 131958.
70. Kyohei Uchida, Yuichiro Kawamoto, Toyoharu Kobayashi, and Hisanaka Ito, Total Synthesis of Applanatumols X and Y, Tetrahedron Lett.2020, 61, 152611.
69. Yuichiro Kawamoto, Fuka Karube, Toyoharu Kobayashi, and Hisanaka Ito, Enantioselective Total Synthesis of Mollebenzylanol A, Org. Lett.2020, 22, 7609-7612.
66. Yuichiro Kawamoto, Daiki Ozone, Toyoharu Kobayashi, and Hisanaka Ito, Enantioselective total synthesis of chondrosterins I and J via catalytic aymmetric intramolecular aldol reaction using chiral diamine catalyst, Euro. J. Org. Chem.2020, 4050-4058.
59. Hideki Abe, Mitsuru Fujimaki, Ena Goto, Akihito Yokosuka, Yoshihiro Mimaki, Toyoharu Kobayashi, and Hisanaka Ito, Total synthesis and determination of the absolute configuration of paralemnolin C and biological studies of eremophilane derivatives, Tetrahedron Lett.2019, 60, 1604-1606.
58. Toyoharu Kobayashi, Iori Takizawa, Ayumu Shinobe, Yuichiro Kawamoto, Hideki Abe, and Hisanaka Ito, Development of a Chiral Diketone Possessing C2 Symmetry: Asymmetric Synthesis and Structure Revision of Guignardone H and I Using Sequential Condensation-6π-Electrocyclization Reactions, Org. Lett.2019, 21, 3008-3012.
57. Yuichiro Kawamoto, Daiki Ozone, Toyoharu Kobayashi, and Hisanaka Ito, Total Synthesis of (±)-Chondrosterin I Using Desymmetric Intramolecular Aldol Reaction, Org. Biomol. Chem.2018, 16, 8477-8480.
56. Toyoharu Kobayashi, Konomi Tanaka, Masako Ishida, Natsumi Yamakita, Hideki Abe, and Hisanaka Ito, Asymmetric Total Synthesis of Pleurospiroketals A and B, Chem. Commun.2018, 54, 10316-10319.
55. Hideki Abe, Mitsuru Fujimaki, Eri Nakagawa, Toyoharu Kobayashi, and Hisanaka Ito, Enantioselective total synthesis of sagittacin E and related natural products, Chem. Commun.2018, 54, 6165-6168.
54. Hideki Abe, Takuma Hikichi, Kosuke Emori, Akihito Yokosuka, Yoshihiro Mimaki, Toyoharu Kobayashi, and Hisanaka Ito, Total Synthesis of Catunaregin and Preliminary Evaluation of its Antitumor Activity, Euro. J. Org. Chem.2018, 1655-1664.
53. Toyoharu Kobayashi, Kotono Yamanoue, Hideki Abe, and Hisanaka Ito, Diastereoselective Total Synthesis of (±)-Toxicodenane A, Euro. J. Org. Chem.2017, 6693-6699.
51. Hideki Abe, Haruhito Tango, Toyoharu Kobayashi, and Hisanaka Ito, Asymmetric total synthesis and revision of absolute configurations of azaphilone derivative felinone A, Tetrahedron Lett.2017, 58, 4296-4298.
50. Toyoharu Kobayashi, Masako Ishida, Kazuhiro Imaida, Hideki Abe, and Hisanaka Ito, Total Synthesis of Pleurolactone, Tetrahedron Lett.2017, 58, 3294-3295.
44. Toyoharu Kobayashi, Kasumi Tokumoto, Yuki Tsuchitani, Hideki Abe, and Hisanaka Ito, Synthetic study of marine diterpenoid aberrarone: stereocontrolled construction of tetracyclic framework, Tetrahedron2015, 71, 5918-5924.
43. Hideki Abe, Yuri Horii, Megumi Hagiwara, Toyoharu Kobayashi, and Hisanaka Ito, Stereoselective synthesis of a highly oxygenated decahydrocyclopenta[g]chromene derivative: the common tricyclic framework of leucosceptrine and leucosesterterpenone, Chem. Commun.2015, 51, 6108-6110.
42. Hideki Abe, Satoko Itaya, Kei Sasaki, Toyoharu Kobayashi, and Hisanaka Ito, Total synthesis of the proposed structure of a polyketide from Phialomyces macrosporus, Chem. Commun.2015, 51, 3586-3589.
41. Hideki Abe, Naohiro Miyagawa, Sho Hasegawa,Toyoharu Kobayashi, Sakae Aoyagi, Chihiro Kibayashi, Tadashi Katoh, and Hisanaka Ito, Directed synthesis of 2-spiroindolines from indole derivatives by formic acid-induced N-acyliminiumion-conjugated diene spirocyclization, Tetrahedron Lett.2015, 56, 921-924.
40. Hideki Abe, Toshihiro Yoshie, Takumi Wagatsuma,Toyoharu Kobayashi, and Hisanaka Ito, Synthetic Study of Afritoxinone A: Stereoselective Construction of Furopyranone Moiety, Heterocycles2015, 90, 706-714.
39. Toyoharu Kobayashi, Yutaro Kon, Hideki Abe, and Hisanaka Ito, Concise Total Synthesis of Albaflavenone utilizing Sequential Intramolecular Aldol Condensation: Determination of Absolute Configuration, Org. Lett.2014, 16, 6397-6399.
38. Hideki Abe, Akira Tezuka, Toyoharu Kobayashi, Hisanaka Ito, Synthesis of Oxygen-Bridged Decahydroazulene Derivatives: Simplified Analogues of Biologically Active Natural Products, Heterocycles2014, 88, 651-662.
37. Toyoharu Kobayashi, Hidenori Shiroi, Hideki Abe, and Hisanaka Ito, Synthetic Study of Presilphiperfolan-8-ol: Construction of the Tricyclo[5.3.1.04,11]undecane Framework Utilizing Intramolecular Aldol Condensation and McMurry Coupling, Chem. Lett.2013,42, 975-976.
36. Hideki Abe, Akimi Sato, Toyoharu Kobayashi, and Hisanaka Ito, Concise Total Synthesis of Spirocurcasone, Org. Lett.2013, 15, 1298-1301. 本論文がSynfacts誌で紹介されました．https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0033-1338712
35. Hideki Abe, Naoki Fukazawa, Toyoharu Kobayashi, and Hisanaka Ito, Indium chloride mediated chlorolactonization: Construction of chlorinated lactone fragments, Tetrahedron2013, 69, 2519-2523.
34. Hideki Abe, Akimi Sato, Shin-ichi Tokishita, Toshihiro Ohta, and Hisanaka Ito, Synthesis of Fluorescence Pyriproxyfen Analogues as Juvenile Hormone Agonist, Heterocycles2011, 83, 1649-1658.
33. Yohei Ueda, Hideki Abe, Kazuo Iguchi, and Hisanaka Ito, Synthetic study of yonarolide: stereoselective construction of the tricyclic core, Tetrahedron Lett. 2011, 52, 3379-3381.
32. Yohei Ueda, Kayoko Iwahashi, Kazuo Iguchi, and Hisanaka Ito, Enantioselective Synthesis of the Tetracyclic Core of Platensimycin, Synthesis2011, 1532-1536.
31. Hisanaka Ito, Mai Matsuoka, Yohei Ueda, Madoka Takuma, Yoshihisa Kudo, and Kazuo Iguchi, Quinolinecarboxylic Acid Based Fluorescent Molecules: Ratiometric Response to Zn2+, Tetrahedron2009, 65, 4235-4238.
30. Hisanaka Ito, Takaya Inoue, and Kazuo Iguchi, Toward the Synthesis of Didemnaketal B: A Convergent Synthesis of the C9-C28 Subunit, Org. Lett.2008, 10, 3873-3876.
22. Junya Iwasaki, Hisanaka Ito, Miwako Aoyagi, Yuki Sato, and Kazuo Iguchi, Briarane-type Diterpenoids from the Okinawan Soft Coral, Pachyclavularia violacea, J. Nat. Prod.2006, 69, 2-6.
21. Hisanaka Ito, Chie Kawabe, and Kazuo Iguchi, Construction of Optically Active Spiroketal by Direct Aldol Reaction, Heterocycles2006, 67, 695-704. (Prof. Trost’s 65th birthday special issue)
20. Azusa Sato, Hisanaka Ito, Midori Okada, Yuko Nakamura, and Takeo Taguchi, Copper-catalyzed addition of γ,γ-dialkoxyallylic zirconium species with imines, Tetrahedron Lett.2005, 46, 8381-8383.
19. Hisanaka Ito, Azusa Sato, and Takeo Taguchi, The Lewis acid promoted reactions of γ,γ-dialkoxyallylic zirconium species with various carbonyl compounds, Tetrahedron2005, 61, 10868-10879.
18. Hisanaka Ito, Yosuke Takenaka, Shouhei Fukunishi, and Kazuo Iguchi, A Practical Preparation of 2-Hydroxymethyl-2-cyclopenten-1-one by Morita-Baylis-Hillman Reaction, Synthesis2005, 3035-3038.
17. Azusa Sato, Hisanaka Ito, and Takeo Taguchi, Highly Regioselective Coupling Reactions of Allylic and Propargylic Alcohol Derivatives with γ,γ-Dialkoxyallylic Zirconium Species via Zr-to-Cu Transmetalation, J. Org. Chem.2005, 70, 709-712.
16. Yasushi Takigawa, Hisanaka Ito, Katsunori Omodera, Minoru Koura, Yasuyuki Kai, Emi Yoshida, and Takeo Taguchi, Diastereoselective Intramolecular Ester Transfer Reaction of N-alkenylcarbamate Derivatives Mediated by Zirconocene-butene Complex. Preparation of a,g-Disubstituted γ-Aminobutyric acid (GABA) Derivatives and 2,4-Disubstituted Pyrrolidine Derivatives, Synthesis2005, 2046-2054.
15. Hisanaka Ito, Mineki Hasegawa, Yosuke Takenaka, Tatsuya Kobayashi, and Kazuo Iguchi, Enantioselective Total Synthesis of (+)-Tricycloclavulone, J. Am. Chem. Soc.2004, 126, 4520-4521.
14. Yasushi Takigawa, Hisanaka Ito, Katsunori Omodera, Maiko Ito, and Takeo Taguchi, Construction of nitrogen-heterocyclic compounds through zirconium mediated intramolecular alkene-carbonyl coupling reaction of N-(o-alkenylaryl)carbamate derivatives, Tetrahedron2004, 60, 1385-1392.
13. Hisanaka Ito, Masami Konishi, and Kazuo Iguchi, Stereoselective Total Synthesis of Preclavulone-A Methyl Ester and Its Diastereomer, Tetrahedron Lett.2004, 45, 1941-1944.
11. Hisanaka Ito, Tatsuya Kobayashi, Mineki Hasegawa, and Kazuo Iguchi, An efficient constructive method for a tricyclic system: an important intermediate for the synthesis of tricycloclavulone, Tetrahedron Lett.2003, 44, 1259-1261.
10. Akio Saito, Hisanaka Ito, and Takeo Taguchi, Intramolecular Diels-Alder Reactions of Ester-Tethered 1,7,9-Decatrienoates: Bis[chloro(methyl)aluminum] trifluoromethanesulfonamide as a Catalyst, Org. Lett.2002, 4, 4619-4621.
9. Barry M. Trost, Vince S. C. Yeh, Hisanaka Ito, and Nadine Bremeyer, Effect of Ligand Structure on the Zinc-Catalyzed Henry Reaction. Asymmetric Syntheses of (-)-Denopamine and (-)-Arbutamine, Org. Lett.2002, 4, 2621-2623.
8. Hisanaka Ito, Katsunori Omodera, Yasushi Takigawa, and Takeo Taguchi, 1 Zirconium-Mediated Intramolecular Ester Transfer Reaction: Synthesis of a-Substituted g-Aminobutyric Acid (GABA) Derivatives, Org. Lett.2002, 4, 1499-1501.
7. Akio Saito, Hisanaka Ito, and Takeo Taguchi, A stereoselective preparation of 1-fluorocyclopropane-1-carboxylate derivatives through radical addition of fluoroiodoacetate to alkenes followed by intramolecular substitution reaction, Tetrahedron2001, 57, 7487-7493.
6. Barry M. Trost, Elliad R Silcoff, and Hisanaka Ito, Direct Asymmetric Aldol Reactions of Acetone Using Bimetallic Zinc Catalysts, Org. Lett.2001, 3, 2497-2500.
5. Barry M. Trost, Hisanaka Ito, and Elliad R Silcoff, Asymmetric Aldol Reaction via a Dinuclear Zinc Catalyst. a-Hydroxyketones as Donors, J. Am. Chem. Soc.2001, 123, 3367-3368.
4. Barry M. Trost and Hisanaka Ito, A Direct Catalytic Enantioselective Aldol Reaction via a Novel Catalyst Design, J. Am. Chem. Soc.2000, 122, 12003-12004.
3. Azusa Sato, Hisanaka Ito, Yusuke Yamaguchi, and Takeo Taguchi, Cu(I)-Assisted carbon-carbon bond forming reactions of γ,γ-dialkoxyallylic zirconium species: A new versatile homoenolate equivalent of propionate, Tetrahedron Lett.2000, 41, 10239-10243.
2. Atsuro Nakazato, Toshihito Kumagai, Kazunari Sakagami, Ryoko Yoshikawa, Yoshiko Suzuki, Shigeyuki Chaki, Hisanaka Ito, Takeo Taguchi, Shigetada Nakanishi, and Shigeru Okuyama, Synthesis, SARs, and Pharmacological Characterization of 2-Amino-3 or 6-fluorobicyclo[3,1,0]hexane-2,6-dicarboxylic Acid Derivatives as Potent, Selective, and Orally Active Group II Metabotropic Glutamate Receptor Agonists, J. Med. Chem.2000, 43, 4893-4909.
1. Azusa Sato, Hisanaka Ito, and Takeo Taguchi, Reaction of γ,γ-Dialkoxyallylic Zirconium Species with Aldehyde As Protected Acryloyl Anion, J. Org. Chem.2000, 65, 918-921.
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